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Additionally, Baker et al. Because changes in lipid and protein oxidation were not observed with budesonide, it was hypothesized that these might be mechanisms by which prednisone induces weight gain. Overall, it seems as though some weight gain may be inevitable for long-term prednisone users regardless of the dose.
Or was the weight gain considered unfavorable — and associated with deleterious body composition changes such as increased fat around the midsection and muscle loss? Results indicated that weight gain-related adverse effects were more likely to be moderate or severe among prednisone users than deflazacort users. If so, were any of these strategies effective?
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